Fondaparinux sodium ( Fondaparinux sodium; PENTA; Arixtra )

Catalog No. M17157 CAS No. 114870-03-0

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Product Name

Fondaparinux sodium
Note

Research use only, not for human use.
Brief Description

Fondaparinux Sodium is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
Description

Fondaparinux sodium is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII).
Synonyms

Fondaparinux sodium; PENTA; Arixtra
Pathway

Others
Target

Other Targets
Recptor

Factor Xa
Research Area

Cardiovascular Disease
Indication

——

CAS Number

114870-03-0
Formula Weight

1729.09
Molecular Formula

C31H44N3Na10O49S8
Purity

98%
Solubility

H2O : ≥ 30 mg/mL 17.26 mM
SMILES

[C@H]1([C@H]([C@@H](O[C@@H]2[C@@H](O[C@H]([C@@H]([C@H]2O)OS(=O)(=O)[O-])O[C@H]2[C@@H]([C@H]([C@H](O[C@@H]2COS(=O)(=O)[O-])OC)NS(=O)(=O)[O-])O)C(=O)[O-])O[C@@H]([C@H]1O[C@@H]1O[C@@H]([C@H]([C@@H]([C@H]1O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COS(=O)(=O)[O-])O)O)NS(=O)(=O)[O-])C(=O)[O-])COS(=O)(=O)[O-])NS(=O)(=O)[O-])OS(=O)(=O)[O-].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+]
Chemical Name

sodium (2S,3S,4R,5R,6R)-6-(((2R,3R,4R,5R,6R)-6-(((2R,3S,4S,5R,6R)-2-carboxylato-4-hydroxy-6-(((2R,3S,4R,5R,6S)-4-hydroxy-6-methoxy-5-(sulfonatoamino)-2-((sulfonatooxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-5-(sulfonatooxy)tetrahydro-2H-pyran-3-yl)oxy)-5-(sulfonatoamino)-4-(sulfonatooxy)-2-((sulfonatooxy)methyl)tetrahydro-2H-pyran-3-yl)oxy)-3-(((2R,3R,4R,5S,6R)-4,5-dihydroxy-3-(sulfonatoamino)-6-((sulfonatooxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4,5-dihydroxytetrahydro-2H-pyran-2-carboxylate

1.Bauer KA. et al..Am J Health Syst Pharm. 2001 Nov 1;58 Suppl 2:S14-7.

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